Schouml;ngruuml;nstrasse Author

Case Report Open Access

Hidden Hypopharyngeal Primary of HPV Associated Lymphoepithelial-Like Carcinoma Presenting with Lymph Node Metastasis

Author(s):

Olivier T Giger and Patrick DubachBurgerspital Solothurn, Schöngrünstrasse

Background: Lymphoepithelial-like carcinoma of the pharynx is a recently described sub-entity of HPV-associated pharyngeal squamous cell carcinoma. This histological entity might become an important differential diagnosis of cervical lymph node metastasis to its well known EBV-associated epipharyngeal counterpart.

Methods and results: We report on a patient presenting with a cervical cystic mass. Clinical findings and fine needle aspiration cytology was compatible with a second branchial arch cyst. Consecutive excision showed a lymph node with poorly differentiated lymphoepithelial-like squamous cell carcinoma, suggestive for a metastasis of an oropharyngeal primary. The patient underwent pandendoscopy with suspected primary in the epi- or oroph... view more»

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