Journal of Sleep Disorders: Treatment and CareISSN: 2325-9639

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Sergio Tufik Author

Subjects of specialization
Psycobiology, Sleep Disorders , Sleep

Affiliation
Department of Psycobiology, Sleep Disorders Center, Universidade Federal de S

Biography

Sergio Tufik, MD, PhD, is a researcher and chairman of the Sleep Studies Center at UNIFESP. Dr. Tufik is also a researcher at the Research Incentive Fund Association (AFIP) in Brazil and at the Brazilian National Council for Scientific and Technological Development (cCNPq). He is a member of the World Association of Sleep Medicine and the European Sleep Research Society, among others.


Publications

Research Article Subscription

Sleep Hypoxemia and Urinary Free Cortisol in Patients with Obstructive Sleep Apnea

Author(s):

Suelem Izumi, Fernando Flexa Ribeiro-Filho, Glaucia Carneiro, Sonia M Togeiro, Sergio Tufik and Maria Teresa Zanella

Objective: This study evaluated the influence of obstructive sleep apnea (OSA) on hypothalamic–pituitary–adrenal (HPA) axis aiming to identify the polysomnographic data associated with cortisol abnormalities.

Methods: Forty-one men referred for suspected OSA underwent polysomnography and were classified according to the apneahypopnea index (AHI) into control group (n=16) and OSA group (n=25). The assessment of the HPA axis function included low-dose (0.25 mg) dexamethasone suppression test, the circadian rhythm of salivary cortisol secretion and the measurement of urinary free cortisol (UFC) excretion in a 24-hour urine collection.

Results: No differences were found be... view moreĀ»

DOI: 10.4172/2325-9639.S1-005

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