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Shohreh Nikoo Author
Subjects of specialization
Affiliation
Applied Microbiology, Applied Microscopy, Applied Mycology, Applied Physiology, Biomedical Research
Immunology Research Center, Iran University of Medical Sciences, Tehran, Iran
Shohreh Nikoo was graduated from Tarbiat Modares University Tehran, IRAN. currently he was working in Immunology Research Center, Iran University of Medical Sciences, Tehran, Iran
Short Communication Open Access
Author(s): Alireza Ghanavatinejad, Mehdi Aleahmad, Mahmood Bozorgmehr, Mohammad-Reza Shokri, Shohreh Nikoo, Maryam Tavakoli, Somaieh Kazemnejad, Fazel Shokri and Amir-Hassan Zarnani
Introduction: One of the most controversial issues in reproductive biology is dealing with the fact that a fully functional immune system in women should simultaneously fight off the invading pathogens and tolerate semi-allograft fetus throughout the pregnancy. Indeed, a successful pregnancy is supposed to remain unresponsive to paternal antigens originating from semi-allograft fetus. Thus far, extensive attempts and studies have been performed to unravel immunosuppressive mechanisms involved in immunological tolerance of gestation. Endometrium undergoes immunological changes to estab- lish tolerance during the onset of pregnancy. Along with gestation initiation, such immune cells as Natural Killer cells (NKs), monocytes, Dendritic Cells (DCs) and T cells are recruited to the endometriu... view more»