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Shougang Wei Author
Subjects of specialization
Affiliation
Obesity, Diabetes
Municipal Key Laboratory of Clinical Epidemiology, School of Public Health, Capital Medical University , Beijing, China.
Biography
Dr. Shougang Wei is currently working as a Professor in the Capital Medical University (China) in the department of Public Health. Dr. Shougang Wei areas of research interests include Obesity, Diabetes etc.,
Publications
Editorial Open Access
Obesity Fitness Expo 2017: Obesity leads to iron retention in the duodenum of mice likely due to increased production of adipose-derived hepcidin- Shougang Wei- Capital Medical University, China
Author(s): Shougang Wei
Obese people and animals have higher rates of iron deficiency (ID) than their normal weight peers. It was still uncertain whether obesity-related ID is a true or functional deficiency of iron. This study was to determine the effects and the possible underlying mechanisms of obesity on duodenal iron absorption and liver iron accumulation. C57BL/6J mice were randomly divided into high-fat diet-induced obese (DIO) group and normal control (NC) group to be fed respectively for 16 weeks. Oral iron absorption was tested by measuring serum iron, liver iron and the retained duodenal iron 90 min after intragastric administration of 57 FeSO4 solution. The protein expression levels of iron transporters in duodenum and liver were evaluated by Western blotting. Hepcidin mRNA levels in the liver and ... view more»
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