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Hindi Endocrinology & Diabetes ResearchISSN: 2470-7570
Shuguang Pang Author
Subjects of specialization
Affiliation
Biology, , Sciences
Callaghan Innovation, Chengdu Institute of Biology, Massey University College of Sciences, Sichuan University, University of Adelaide Faculty of Sciences
Biography
Callaghan Innovation, Chengdu Institute of Biology, Massey University College of Sciences, Sichuan University, University of Adelaide Faculty of Sciences
Guangdong Medical Association, Guangzhou First People's Hospital, Sun Yat-sen University of Medical Sciences
Publications
Review Article Subscription
The Interaction between Metformin and Bile Acids in Metabolic Disease
Author(s): Jianting Li, Yang Liu and Shuguang Pang
Objective: To review the function of bile acids and the mechanism of metformin in lipid and glucose metabolism, and the interaction between metformin and bile acids.
Methods: PubMed and Google Scholar were searched using terms such as bile acid, lipid, glucose, metformin and type 2 diabetes. Additional relevant references were identified by reviewing the reference lists of articles.
Results: Bile acids are important molecules of regulating glucose and lipid metabolism through FXR and TGR5, while metformin through AMPK signaling pathway. Regulator role of metformin in glucose and lipid metabolism might be associated with bile acid metabolism.
Conclusions: Metformin as a welcomed antidiabetic dru... view more»
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