Suelem Izumi Author
Subjects of specialization
Affiliation
Endocrinology, Metabolism
Department of Medicine, Division of Endocrinology, Universidade Federal de S
Suelem Izumi Graduated in Medicine from the Federal University of Pará. Residency in Internal Medicine at Hospital Ofir Loyola. Medical Residency in Endocrinology and Metabolism at the João de Barros Barreto University Hospital. Specialist in Endocrinology and Metabolism by the Brazilian Society of Endocrinology and Metabolism. Specialization in Nutrology by the Brazilian Association of Nutrology. Doctorate in Medicine from the Federal University of São
Research Article Subscription
Author(s): Suelem Izumi, Fernando Flexa Ribeiro-Filho, Glaucia Carneiro, Sonia M Togeiro, Sergio Tufik and Maria Teresa Zanella
Objective: This study evaluated the influence of obstructive sleep apnea (OSA) on hypothalamic–pituitary–adrenal (HPA) axis aiming to identify the polysomnographic data associated with cortisol abnormalities.
Methods: Forty-one men referred for suspected OSA underwent polysomnography and were classified according to the apneahypopnea index (AHI) into control group (n=16) and OSA group (n=25). The assessment of the HPA axis function included low-dose (0.25 mg) dexamethasone suppression test, the circadian rhythm of salivary cortisol secretion and the measurement of urinary free cortisol (UFC) excretion in a 24-hour urine collection.
Results: No differences were found be... view moreĀ»