Sukanya Suresh Author

Editorial Open Access

Erythropoietin modulates bone marrow stromal cell differentiation

Author(s):

Sukanya Suresh

Erythropoietin is important for bone marrow biological process and glycoprotein receptor on non-erythroid cells as well as bone marrow stromal cells suggests general effects of glycoprotein. Tg6 mice with chronic glycoprotein overexpression have a high hematocrit, reduced trabeculate and plant tissue bone and bone marrow adipocytes, and shriveled bone morphogenic supermolecule a pair of driven position bone and adipocyte formation. glycoprotein treatment (1 200 IU•kg–1) for ten days equally exhibit raised hematocrit, reduced bone and bone marrow adipocytes while not raised osteoclasts, and reduced bone morphogenic supermolecule sign within the bone marrow. apparently, endogenous glycoprotein is needed for traditional differentiation of bone marrow stromal cells to osteoblasts... view more»

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