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Hindi Journal of Diagnostic Techniques and Biomedical AnalysisISSN: 2469-5653
Takako Yoshioka Author
Subjects of specialization
Affiliation
Tuberculosis; BCG; Infant; PCR; Granuloma; Osteomyelitis
Department of Molecular and Cellular Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan
Biography
| Takako Yoshioka Department of Molecular and Cellular Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan |
Publications
Research Article Subscription
Bacillus Calmette-Gu�rin (BCG) Vaccine-Induced Disease in Healthy Infants: Identification of BCG Gene from Formalin-Fixed Paraffin-Embedded Tissue
Author(s): Takako Yoshioka, Junichiro Nishi, Kiyofumi Ohkusu, Kazuhito Hatanaka, Sohsuke Yamada, Kazuhiko Nakame, Yoshifumi, Kawano, Tatsuru Kaji, Akihide Tanimoto
Background: Bacillus Calmette-Guérin (BCG) vaccineinduced systemic complication is rare but localized skin lesion develops in the site of inoculation in healthy infants.
Methods: In this report, we described three cases of BCG vaccineinduced skin lesions in healthy immunocompetent infants and a method of identification of BCG gene by polymerase chain reaction (PCR) form fresh frozen of formalin-fixed and paraffinembedded tissue samples.
Results: These cases had a history of BCG vaccination but no family history of tuberculosis and no contact with patients of tuberculosis. Two cases developed cutaneous granuloma in the axilla of ... view more»
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