Terence Kin-Wah Lee Author
Subjects of specialization
Affiliation
Gastroenterology, Hepatology, Stem Cells
Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
Editorial Open Access
Author(s): Bowie Yik Ling Cheng, Irene Oi Lin Ng, and Terence Kin-Wah Lee
Interleukin-1 receptor-associated kinase (IRAK) family consistsof four members: IRAK1, IRAK2, IRAK3/M and IRAK4. They are key downstream mediators of toll-like receptor (TLR) and interleukin-1 receptor (IL1R) pathways.In particular, TLR, a family of transmembrane pattern recognition receptor (PRR), play a crucial role in the induction of innate and adaptive immune responds against microbial infection, tissue injury and also cancer.
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