Thuy Tran Author
Subjects of specialization
Affiliation
cancer, cancer oncology, Carcinogenesis
Section of Medical Oncology, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
Tran is an Instructor of Medicine (Medical Oncology) and cares for patients with melanoma and renal cell cancers at Smilow Cancer Hospital in New Haven and in Smilow Guilford. She completed her residency in Internal Medicine at Yale-New Haven Hospital and participated in the ABIM Physician-Scientist Research Pathway. She received her MD and PhD degrees from Vanderbilt University School of Medicine.
Case Report Open Access
Author(s): Ana Luisa Perdigoto, Thuy Tran, Natalie Patel, Pamela Clark, Kanchi Patell, Angeliki M Stamatouli, Vikram Reddy, James Clune, Kevan C Herold, Marie E Robert and Harriet M Kluger
Checkpoint inhibitor immunotherapy has significantly advanced treatment of a growing number of advanced malignancies. A consequences of immune system activation that leads to tumor cell destruction by checkpoint inhibitor therapy is the development of immune-related adverse events, some of which can be life threatening. There are limited data on the use of checkpoint inhibitor therapy in patients with preexisting autoimmunity owing to concerns that underlying autoimmune disease may be exacerbated by checkpoint inhibitor treatment. Decisions to treat these patients are made after careful consideration of the risks and benefits of treatment. We describe a patient with active and severe ulcerative colitis with metastatic melanoma who underwent elective cole... view moreĀ»