Spanish 
Chinese 
Russian 
German 
French 
Japanese 
Portuguese 
Hindi Journal of Clinical & Experimental OncologyISSN: 2324-9110
Ugoeze Donatus Author
Subjects of specialization
Affiliation
Glycolysis, Oxidative phosphorylation, Cancer progression
School of Biomedical Science, Faculty of Health Science, Ebonyi State University, Nigeria
Biography
Ugoeze Donatus was working at School of Biomedical Science, Faculty of Health Science, Ebonyi State University, Nigeria. He has more than 40 publications. His current research area related to Cancer progression.
Publications
Review Article Subscription
Metabolic Basis of Treatment Failures; Autophagy and Malignant Cancer Progression
Author(s): Maxwell Omabe1, Martin Ezeani and Ugoeze Donatus
Cells use a number of pathways to generate energy and synthesize cellular building blocks including lipids, carbohydrates and nucleotides. Alterations in metabolic pathways have been implicated in many pathophysiological conditions. This mechanism is exploited by both resident epithelial cancer cells and the fibroblast. Indeed, cancer and normal cells differ dramatically in terms of their energy requirements and use of metabolic pathways. Mitochondrial dysfunction and metabolic impairment contribute immensely to chemotherapeutic resistance and metastatic cancer progression through signaling pathw... view more»
Google Scholars / Researchers Sites
