Advanced Biomedical Research and Innovation

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Vakhtang Barbakadze Author

v.barbakadze@tsmu.edu

Subjects of specialization
Applied Microbiology, Applied Microscopy, Applied Mycology, Applied Physiology, Biomedical Research

Affiliation
Tbilisi State Medical University, Georgia

Biography

Vakhtang Barbakadze has his expertise in isolation and structure elucidation of biologically active plant polysaccharides and polyethers. In 1978 and 1999 he has completed his PhD and DSci, respectively. He is the Head of Department of Plant Biopolymers at the Tbilisi State Medical University Institute of Pharmacochemistry. In 1996 and 2002 he has been a visiting scientist at Utrecht University (The Netherlands) by University Scholarship and The Netherlands organization for scientific research (NWO) Scholarship Scientific Program, respectively. He has published more than 100 papers in reputed journals. In 2004 he was Georgian State Prize Winner in Science and Technology.

Publications

Short Communication Open Access

Sugar based biopolymers: Poly(Sugar Acid) – Poly[3-(3,4-dihydroxyphenyl) Glyceric Acid] from medicinal plants of boraginaceae family, its synthetic analogues and therapeutic efficacy

Author(s):

Vakhtang Barbakadze

Sugar based bio-polymers have widely used in medicine and pharmaceutics. According to data of liquid-state 1H, 13C NMR, 2D 1H/13C HSQC, 2D DOSY and solid-state 13C NMR spectra the main chemical constit¬uent of high molecular (>1000 kDa) water-soluble preparations from medicinal plants of Symphytum asperum, S. caucasicum, S. officinale, S. grandiflorum, Anchusa italica, Cynoglossum officinale and Borago officinalis was found to be poly[oxy-1-carboxy-2-(3,4-dihydroxyphenyl)ethylene] or poly[3-(3,4-dihydroxyphenyl)glyceric acid] (PDPGA). The polyoxyethylene chain is the backbone of this regular polymer with a residue of 3-(3,4-dihydroxyphenyl)glyceric acid as the repeating unit. PDPGA as 3,4-dihydroxyphenyl derivative of poly(2,3-glyceric acid ether) belongs to a class of poly(sugar... view more»

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