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Hindi Cell Biology: Research & TherapyISSN: 2324-9293
Vera Grotheer Author
Subjects of specialization
Affiliation
Biochemistry and Molecular Biology,Cell Cloning,Cell Regeneration,Cell Regeneration,Cell therapy
Department of Trauma and Hand Surgery, Medical Faculty, Heinrich-Heine-University, Moorenstr. 5, 40225 D
Biography
Vera Grotheer is currently working in Department of Trauma and Hand Surgery, Medical Faculty, Heinrich-Heine-University, Moorenstr. 5, 40225 Düsseldorf, Germany. He has international experience on various programs, and also contributed and participated in different countries for diverse fields of study. Research interests reflect in wide range of publications in various national and international journals.
Publications
Research Article Open Access
New Insights into the Tissue Homeostasis between TIMP and MMP in Dupuytren’s Disease
Author(s): Annika Borgschulze, Benita Sahlender, Tim Lögters, Joachim Windolf and Vera Grotheer
Dupuytren’s disease is a fibrotic disorder of the palmar fascia, leading to a functional restriction of the affected finger. The etiological causes of Dupuytren’s Disease are multifactorial, with a genetic disposition concerning predominantly men in the middle age. In, this study on the one hand gene expression was analysed in Dupuytren’s tissue directly after surgery to determine the balance between the tissue inhibitors of matrix metalloproteinases and the matrix metalloproteinases (TIMP/MMP). And on the other hand Dupuytren’s fibroblasts were preincubated with nterleukin-1β (Il-1β) and transforming growth factor-β (TGF-β) to analyze wound healing characteristics. Our data suggest that Dupuytren’s fib... view more»
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