Vesna Popovska Author

Special Issue Article Open Access

Ethical challenges in pediatric neurology clinical trials

Author(s):

Vesna Popovska

Abstract
During the last decade, number of clinical trials have been offered to pediatric patients with neurological disorders.

 

Dravet syndrome (DS) or severe myoclonic epilepsy in infancy is one of the most well-known disorders of the epileptic encephalopathies. DS is a highly treatment-resistant and refractory epilepsy syndrome. Establishment of a seizure free condition in affected children, even with anticonvulsant drug polypharmacy, is extremely rare.

 

Duchenne muscular dystrophy (DMD) is a disabling and life-threatening X-linked genetic disorder affecting males. Boys with DMD develop progressive proximal muscle weakness that leads to deterioration of ambulation, wheelchair dependency, and eventual... view more»

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