Clinical Oncology: Case Reports

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Vikram Reddy Author

vikram.reddy@yale.edu

Subjects of specialization
cancer, cancer oncology, Carcinogenesis

Affiliation
Section of Endocrinology, Virginia Commonwealth University, Richmond, Virginia, USA

Biography

"Vikram Reddy, MD, PhD, is a fellowship-trained colon and rectal surgeon. He specializes in advanced laparoscopic management of colon and rectal diseases; screening and laparoscopic management of colon cancer; screening and management of rectal cancer (including laparoscopic sphincter preserving surgery and Transanal Endoscopic Microsurgery (TEMS); laparoscopic management of complicated or uncomplicated diverticulitis; management of inflammatory bowel disease (including laparoscopic bowel resection and ostomy, laparoscopic proctocolectomy, and J-pouch for ulcerative colitis); laparoscopic management of polyposis syndromes and disorders of continence."

Publications

Case Report Open Access

Elective Colectomy in a Patient with Active Ulcerative Colitis and Metastatic Melanoma Enabling Successful Treatment with Immune Checkpoint Inhibitors

Author(s):

Ana Luisa Perdigoto, Thuy Tran, Natalie Patel, Pamela Clark, Kanchi Patell, Angeliki M Stamatouli, Vikram Reddy, James Clune, Kevan C Herold, Marie E Robert and Harriet M Kluger

Checkpoint inhibitor immunotherapy has significantly advanced treatment of a growing number of advanced malignancies. A consequences of immune system activation that leads to tumor cell destruction by checkpoint inhibitor therapy is the development of immune-related adverse events, some of which can be life threatening. There are limited data on the use of checkpoint inhibitor therapy in patients with preexisting autoimmunity owing to concerns that underlying autoimmune disease may be exacerbated by checkpoint inhibitor treatment. Decisions to treat these patients are made after careful consideration of the risks and benefits of treatment. We describe a patient with active and severe ulcerative colitis with metastatic melanoma who underwent elective cole... view more»

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