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Hindi Journal of Applied Bioinformatics & Computational BiologyISSN: 2329-9533
Wedson Gomes da Silveira Author
Subjects of specialization
Affiliation
Image Processing , Computer Graphics , Electric Motors , Algorithms , Bioinformatics
Unidade de Biotecnologia, University of Ribeirao Preto, Ribeirao Preto SP, Brazil
Biography
Graduated in Electrical Engineering with Eng Computation certificate from the Federal University of Uberlândia (2010), Master in Computer Graphics from the Federal University of Uberlândia UFU (2013). Doctorate in Biotechnology from the University of Ribeirão Preto UNAERP (2017). He is currently a professor at the Federal Center for Technological Education of Minas Gerais CEFETMG. Has experience in Computer Science and Engineering, with an emphasis on Programming Languages, acting on the following subjects: Bioinformatics.
Publications
Research Article Open Access
Comparative Study of Canine and Human miRNAs and CpG Islands
Author(s): Wedson Gomes da Silveira, Edilson Carlos Caritá, Ana L Fachin and Mozart Marins
MicroRNA (miRNA) has been recognized as a major factor in the regulation of gene expression in mammalian species and aberrant DNA methylation of tumor suppressor miRNAs due to CpG Island. Hypermethylation is emerging as another common mechanism of cancer. Because of experimental identification of miRNAs and their targets is difficult, comparative computational analysis is a popular method to identify new miRNAs and their associated targets. In this manuscript, we have performed a comparative analysis of the canine and human genome in order to find new miRNAs associated to CpG Islands. Human and canine miRNAs and genomes were obtained from mirBase and GenBank respective llythe genomes. A total of 67 miRNAs with nearby CGI were identified in the canine genome and 178 in the human genome, ... view more»
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