Zakaria A El-Khyat | Author | SciTechnol

Zakaria A El-Khyat Author

Subjects of specialization
Biochemistry and Molecular Biology,Biophysics,Bioenergy,Hematology,Cell Motility

Affiliation
Medical Biochemistry Department, NRC, Cairo, Egypt

Biography

Zakaria A El-Khyat is currently working in Medical Biochemistry Department, NRC, Cairo, Egypt. He has international experience on various programs, and also contributed and participated in different countries for diverse fields of study. Research interests reflect in wide range of publications in various national and international journals.

Publications

Research Article Subscription

Cannabis resin extract in Parkinson's disease: Behavioral, Neurochemical, and Histological Evaluation

Author(s):

Shaimaa A ElShebiney, Ezzeddein S El-Denshary, Omar ME Abdel-Salam, Neveen A Salem, Zakaria A El-Khyat, Nermeen E Shaffie and Dalaal M Abdallah

Cannabis sativa (Family Cannabaceae, L.) has been used in China and India for thousands of years as a medicine. The main active constituents of cannabis are Δ 9 -tetrahydrocannabinol (THC), cannabinol (CBN) and cannabidiol (CBD). Currently, THC and CBD are being carefully used in conditions, such as multiple sclerosis, cancer pain, and chemotherapy associated emesis. The cannabinoid 1 receptor (CB1R) is considered responsible for most THC effects involving sedation, analgesia, hypothermia, catalepsy, and euphoria . CB1Rs are abundantly distributed in the basal ganglia , where they are co-localized with both dopamine (D)1 and 2 receptors on striatonigral dynorphin/substance P and striatopallidal enkephalinergi... view more»

DOI: 10.4172/2324-9293.1000112

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