Journal of Otology & RhinologyISSN: 2324-8785

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Research Article, J Otol Rhinol Vol: 3 Issue: 4

Comparison of Neuropeptide Innervation in Allergic and Nonallergic Rhinitis

Ulas Eraydin1, Ceren Gunel2*, Leyla Didem Kozaci3, Muhan Erkus4 and H Sema Basak5
1Ardahan Kahta State Hospital, Aydin, Turkey
2Department of Otolaryngology-Head and Neck Surgery, Adnan Menderes University Medical School Hospital, Aydin, Turkey
3Department of Medical Biochemistry, Adnan Menderes University Medical School Hospital, Aydin, Turkey
4Department of Medical Pathology, Adnan Menderes University Medical School Hospital, Aydin, Turkey
5Department of Otolaryngology-Head and Neck Surgery, Adnan Menderes University Medical School Hospital, Aydin, Turkey
Corresponding author : Ceren Gunel
Adnan Menderes Universitesi Tip Fakultesi Hastanesi KBB AD, Aytepe Mevkii, 09100, Aydin, Turkey
Tel: +90-533-7175693; Fax: + 90-256-2182037
E-mail: [email protected]
Received: April 10, 2014, Accepted: July 18, 2014 Published: July 23, 2014
Citation: Ulas Eraydin, Ceren Gunel, Leyla Didem Kozaci, Muhan Erkus, H Sema Basak (2014) Comparison of Neuropeptide Innervation in Allergic and Nonallergic Rhinitis. J Otol Rhinol 3:4. doi:10.4172/2324-8785.1000166

Abstract

Comparison of Neuropeptide Innervation in Allergic and Nonallergic Rhinitis

Background: Rhinitis can be induced by different mechanisms and involves several etiological agents. It is important to differentiate between allergic rhinitis (AR) and nonallergic rhinitis (NAR), as management differs for each.

Objective: We aimed to study the several biomarkers of allergic rhinitis and nonallergic rhinitis to investigate their potential as outcome measures in clinical intervention trials.

Materials and Methods: All study groups were compared in terms of mucociliary clearance time, air flow level, and various neuropeptids in nasal fluid. All groups were evaluated for asthma by a respiratory medicine specialist performing pulmonary function testing.

Keywords: Allergic rhinitis;Ig E; IL-5;Nonallergic rhinitis; VIP; SP; CGRP

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