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Journal of Otology & RhinologyISSN: 2324-8785

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Research Article, J Otol Rhinol Vol: 1 Issue: 2

Expression of STK15, EGFR, p53 and p16INK4A by Squamous Cell Carcinoma (SCC) of the Nasal Cavity and the Paranasal Sinuses

Abstract

Expression of STK15, EGFR, p53 and p16INK4A by Squamous Cell Carcinoma (SCC) of the Nasal Cavity and the Paranasal Sinuses

Cancers of the nasal cavity or the paranasal sinuses have a low prevalence and incidence. In addition the presentation in various subsites of the nose and the paranasal sinuses and the existence of multiple tumor histopathologies complicate an execution of a study. These cancers represent 0.5% of all malignant neoplasms and 3% of head and neck cancers. 50% of the nasal cancers are squamous cell carcinomas (SCC).

Keywords: Nasal squamous cell carcinoma; STK15; EGFR; p53; p16

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