Journal of Applied Bioinformatics & Computational BiologyISSN: 2329-9533

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Research Article, J Appl Bioinform Comput Biol Vol: 3 Issue: 2

Network Topology and Functional Analysis of Genes in Ocular Disorders

Umadevi Subramanian and Rajakumar Sundaram*
Department of Marine Biotechnology, Bharathidasan University, Tiruchirappalli,India
Corresponding author : Dr. Rajakumar S
Assistant Professor, Department of Marine Biotechnology, Bharathidasan University, Tiruchirappalli – 620 024, Tamil Nadu, India
Tel: +919600342290
E-mail: [email protected]
Received: March 21, 2014 Accepted: July 25, 2014 Published: July 28, 2014
Citation: Subramanian U, Sundaram R (2014) Network Topology and Functional Analysis of Genes in Ocular Disorders. J Appl Bioinform Comput Biol 3:2. doi:10.4172/2329-9533.1000109

Abstract

Most common genetic disorders have a complex inheritance and they are results of mutations in many genes, each gene contribute effects to the disease. The diseases belonging to the same disease class do not always share common disease genes; share a protein-protein interaction and gene ontology biological process with different diseases. This study focused on analyzing the genetic complexity of ocular disorders.

Keywords: Ocular disorders; Overlapping genes; Network; Statistical analysis; Gene function

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