Perspective, Biomater Med Appl Vol: 7 Issue: 1
An Overview of Carcinogens and Prevention to Exposure
Department of Chemistry, Purdue University, West Lafayette, USA
Received date: 27 February, 2023, Manuscript No. BMA-23-93083;
Editor assigned date: 01 March, 2023, Pre QC No. BMA-23-93083(PQ);
Reviewed date: 17 March, 2023, QC No. BMA-23-93083;
Revised date: 27 March, 2023, Manuscript No: BMA-23-93083(R);
Published date: 04 April, 2023, DOI: 10.35248/ 2577-0268.100505
Citation: Jones B (2023) An Overview of Carcinogens and Prevention to Exposure. Biomater Med Appl 12:1.
Carcinogenic substances are agents or compounds that have the potential to cause cancer by inducing changes in DNA or disrupting cellular processes. Exposure to these substances can increase the risk of developing cancer by damaging the genetic material and triggering uncontrolled cell growth. Some common carcinogens include tobacco smoke, ultraviolet radiation, asbestos, benzene, and certain chemicals used in food processing and manufacturing. Tobacco smoke is one of the most well-known and preventable causes of cancer. The smoke contains more than 70 known carcinogens, including Polycyclic Aromatic Hydrocarbons (PAHs) and nitrosamines. PAHs are formed when organic matter, such as tobacco, is burned, and can cause mutations in DNA that lead to cancer. Nitrosamines are formed when tobacco is cured and can damage DNA by creating abnormal chemical bonds. Ultraviolet radiation from the sun or tanning beds is another common carcinogen. UV rays damage the DNA in skin cells, leading to mutations that can cause skin cancer. Exposure to UV radiation is responsible for the majority of cases of melanoma, a deadly form of skin cancer.
Asbestos is a naturally occurring mineral that was widely used in construction and manufacturing until it was banned in many countries due to its carcinogenic properties. Asbestos fibers are small and can be inhaled; causing damage to the lungs that can lead to lung cancer and mesothelioma, a rare cancer of the lining of the lungs and other organs. Benzene is a chemical used in the production of plastics, resins, and synthetic fibers, as well as in gasoline and other fuels. Exposure to benzene can lead to leukemia and other blood cancers by damaging the DNA in blood cells and disrupting the normal process of cell growth and division. Certain chemicals used in food processing and manufacturing, such as acrylamide and nitrites, have also been identified as carcinogens. Acrylamide is formed when starchy foods are cooked at high temperatures, such as in frying or baking. Nitrites are used as preservatives in processed meats and can form cancercausing compounds when they interact with amino acids in the meat.
The risk of developing cancer from exposure to carcinogens depends on a variety of factors, including the dose and duration of exposure, the individual's genetics, and other environmental factors. Some people may be more susceptible to the effects of carcinogens due to genetic factors or a weakened immune system. Preventing exposure to carcinogens is key to reducing the risk of developing cancer. This can include avoiding tobacco smoke, wearing protective clothing and sunscreen when outdoors, and using caution when handling chemicals or working in industries with high levels of exposure. In addition, a healthy lifestyle that includes regular exercise and a balanced diet can help reduce the risk of cancer by supporting a strong immune system and reducing inflammation in the body. Overall, carcinogens are substances that have been shown to cause cancer by damaging DNA and disrupting cellular processes. By taking steps to reduce exposure to these substances, individuals can reduce their risk of developing cancer and promote overall health and wellbeing.