Journal of Pharmaceutics & Drug Delivery ResearchISSN: 2325-9604

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Review Article, J Pharm Drug Deliv Res Vol: 6 Issue: 2

Application of Ultrasound to Pharmaceutical Industry : An Overview

Shekar HS1, Rajamma AJ2* and Sateesha SB3

1Department of Pharmacy, VIPS, Bangalore, India

2Department of Pharmacy, KLEUs College of Pharmacy, Bangalore-560010, India

3Department of Pharmacy, Acharya & B.M. Reddy College of Pharmacy, Bangalore-560107, India

*Corresponding Author : Dr. Rajamma AJ
Professor and HOD, Department of Pharmacy, KLEUs College of Pharmacy, Bangalore-560010, India
Tel: 09731016717

Received: April 12, 2017 Accepted: April 28, 2017 Published: May 04, 2017

Citation: Shekar HS, Rajamma AJ, Sateesha SB (2017) Application of Ultrasound to Pharmaceutical Industry: An Overview. J Pharm Drug Deliv Res 6:2. doi: 10.4172/2325-9604.1000165


The term “ultrasound” means vibrations similar to sound waves with a frequency higher than 20 kHz. US waves, apart from sharing the usual properties of sound, they also show some new properties owing to high energies. This makes ultrasonic waves to find use in engineering, material science and medicine. The ability to tune the frequency and amplitude of ultrasonic waves makes this technology attractive in pharmaceutical field also. Ultrasound is a promising technology with wide applications in pharmacy such as in controlling particle size, controlled crystallization, production of nano materials, enhancing the solubility of poorly soluble drug candidates. Furthermore, ultrasound can be used in effluent treatment, separation and concentration of particulate sub-populations based on dimensions and physical properties. US technology is also found useful in processing and formulating delicate biomolecules, such as proteins and nucleic acids because it ensures structural integrity of the molecules.

Keywords: Ultrasound; Ultrasonic waves; Nano materials; Solubility enhancement; Biomolecules

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