International Journal of Mental Health & PsychiatryISSN: 2471-4372

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Research Article, Int J Ment Health Psychiatry Vol: 2 Issue: 4

Deficient Integration of Short and Long Term Memory in Individuals with Schizophrenia

Victor Marinho1,2*, Kaline Rocha1, Francisco Magalhaes1, Jessica Ribeiro1, Thomaz de Oliveira1,2, Pedro Ribeiro1,3, Fernanda Sousa4, Monara Nunes4, Valécia Carvalho4, Victor Hugo Bastos4, Bruna Velasques3 and Silmar Teixeira1
1Brain Mapping and Plasticity Laboratory, Federal University of Piauí (UFPI), Parnaíba, Brazil
2Genetics and Molecular Biology Laboratory, Federal University of Piauí, Parnaíba, Brazil
3Brain Mapping and Sensory Motor Integration, Institute of Psychiatry of Federal University of Rio de Janeiro (IPUB/UFRJ), Brazil
4Brain Mapping and Functionality Laboratory, Federal University of Piauí (LAMCEF) (UFPI), Parnaíba, Brazil
Corresponding author : Francisco Victor Costa Marinho
Brain Mapping and Plasticity Laboratory- Av. Sao Sebastiao no 2819 – Nossa Sra. de Fatima –Parnaiba, PI, CEP: 64202-020, Brazil
Tel: +55 86 988374232
E-mail:
[email protected]
Received: August 16, 2016 Accepted: September 09, 2016 Published: September 12, 2016
Citation: Marinho V, Rocha K, Magalhaes F, Ribeiro J, de Oliveira T, et al. (2016) Deficient Integration of Short and Long Term Memory in Individuals with Schizophrenia. Int J Ment Health Psychiatry 2:4. doi:10.4172/2471-4372.1000134

Abstract

A deficiency in processing, retaining and consolidating information in the short and long term memory is observed in schizophrenics. Dopaminergic levels and synchronism of neural inputs in coding of events interpreted by the central nervous system appear to be related to this deficiency. However, there is limited understanding on the specific memory functions through a specialized network and focused on areas of the brain. Therefore, we conducted a literature search in the databases PubMed, Scielo, Lilacs and Bireme to demonstrate the disintegration in the processing of information attributed to failures in connectivity between hippocampal neural circuits with the various encephalic areas in schizophrenic patients. The literature reports that schizophrenics, among other causes, have deficiencies in cortico-hippocampal connections that participating in separation of time pattern, processing and consolidation of memory.

Keywords: Schizophrenia; Working memory; Short-term memory; Long-term memory; Hippocampus

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