Journal of Otology & RhinologyISSN: 2324-8785

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Review Article,  J Otol Rhinol Vol: 4 Issue: 6

Genetic Aspects of Allergic Rhinoconjunctivitis: A Review

Arzu Didem Yalcin1*, Emre Ozkan2, Fusun Uzunoglu3 and Kemal Kiraz4
1Department of Allergy and Clinical Immunology, Antalya, Turkey
2Anatolia Hospital Department of Pulmonary Medicine, Antalya, Turkey
3Dunya Goz Hastanesi Department of Ophthalmology, Istanbul, Turkey
4Antalya Education and Training Hospital, Department of Pulmonary Medicine, Antalya, Turkey
Corresponding author : Dr. Arzu Didem Yalcin, MD
Internal Medicine, Allergy and Clinical Immunology, Genomics Research Center, Academia Sinica,11529, Taiwan and Antalya Education and Training Hospital. Department of Allergy and Clinical Immunology, 07070, Antalya, Turkey
Received: September 05, 2015 Accepted: November 05, 2015 Published: November 09, 2015
Citation: Yalcin AD, Ozkan E, Uzunoglu F, Kiraz K (2015) Genetic Aspects of Allergic Rhinoconjunctivitis: A Review. J Otol Rhinol 4:6. doi:10.4172/2324-8785.1000258


Allergic rhinoconjunctivitis (ARC) is a very common clinical entitiy effecting 20-30% of the population, with multiple allergies accompanying the situation as high as 54%. Being a type I hypersensitivity reaction to allergens, the symptoms of rhinitis and conjunctivitis mostly overlap, sharing common etiopathogenic properties. Allergic rhinitis is an inflammation of the nasal mucosa caused by an immune reaction mediated by immunoglobulin (Ig) E antibodies. Clinically, it is characterized by sneezing, rhinorrhea, nasal obstruction, and itching of the nasal membranes, pharynx, and soft palate. Allergic rhinitis is the most prominent of allergic diseases and is accompanied by bronchial asthma and especially ocular symptoms.

Keywords: Genetic Aspects; Allergic rhinoconjunctivitis

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