Journal of Otology & RhinologyISSN: 2324-8785

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Research Article, J Otol Rhinol Vol: 7 Issue: 1

Incidence of Sphenoid Sinus Mucoceles after Endoscopic Transsphenoidal Approach with Sphenoid Obliteration

Anthony Yang1, Sean Mckee1, Katelyn Stepan1, Neeraja Konuthula1, Roya Nazarian1, Maximiliano Sobrero1, Alok Saini1, Kalmon D Post2 and Alfred Marc C Iloreta1*

1Department of Otolaryngology - Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA

2Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA

*Corresponding Author : Alfred Marc C Iloreta, MD
Department of Otolaryngology–Head and Neck Surgery, Mount Sinai Medical Center, One Gustave L. Levy Place, Box 1189, New York, NY 10029–3136, USA
Tel: 212-241-9140
Fax: 212-831-3700

Received: August 21, 2017 Accepted: January 05, 2018 Published: January 13, 2018

Citation: Yang A, Mckee S, Stepan K, Konuthula N, Nazarian R, et al. (2018) Incidence of Sphenoid Sinus Mucoceles after Endoscopic Transsphenoidal Approach with Sphenoid Obliteration. J Otol Rhinol 7:1. doi: 10.4172/2324-8785.1000334


Objective: Sphenoid sinus mucocele is a rare complication of transsphenoidal surgery and can present clinically many years after the initial surgery. Although the formation of sphenoid sinus mucocele has been previously described in the literature as case reports, there is no information demonstrating the incidence of sphenoid sinus mucocele after sphenoid obliteration in a large series. This study aims to determine the incidence of sphenoid sinus mucocele formation and other postoperative complications following transsphenoidal surgery with fat obliteration.

Methods: A retrospective review was performed of patients who underwent sphenoid obliteration with fat after Transsphenoidal approach for pituitary adenoma by two surgeons at our institution from 2001 to 2003. Follow-up records up to 2015 were obtained for these patients. Data collected included demographics, operation performed, sphenoid sinus obliteration method, reconstruction method, follow-up period, postoperative complications, recurrence and residual disease.

Results: Of the 95 patients who underwent Transsphenoidal approach and sphenoid obliteration with fat, 27 patients developed postoperative complications. None had sphenoid sinus mucocele formation. Recurrence of disease occurred in 11.6% of patients. Residual disease was present in 7.4% of patients. Complications included sinusitis, hematoma, hyponatremia, acromegaly and postoperative need for the placement of a ventriculoperitoneal shunt.

Conclusion: Sphenoid sinus mucocele formation is a rare complication following transsphenoidal surgery with fat obliteration with an estimated incidence of less than 1.1%. Further studies with more cases are needed to accurately establish the incidence.

Keywords: Sphenoid mucocele; Obliteration; Incidence; Transsphenoidal; Pituitary; Fat; Long-term

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