Journal of Otology & RhinologyISSN: 2324-8785

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Case Report, J Otol Rhinol Vol: 7 Issue: 2

Langerhans Cell Histiocytosis in Temporal Bone: Case Report

Ahmed Abdelrahman Abdelziz1*, Nasr Mohamed M Osman2 and Mariana F Gayyed3

1Department of Otorhinolaryngology, El Minia University Hospital, Egypt

2Department of Radiology, El Minia University Hospital, Minia, Egypt

3Department of Pathology, EL Minia Faculty of Medicine, EL Minia, Egypt

*Corresponding Author : Ahmed Abdelrahman Abdelaziz
Lecturer of Otorhinolaryngology, El Minia University Hospital, El Minia, Egypt
E-mail: [email protected]

Received: Janaury 15, 2018 Accepted: February 02, 2018 Published: February 10, 2018

Citation: Abdelziz AA, Osman NMM, Gayyed MF (2018) Langerhans Cell Histiocytosis in Temporal Bone: Case Report. J Otol Rhinol 7:2. doi: 10.4172/2324-8785.1000339


Langerhans cell histiocytosis (LCH) is a rare disorder characterized by uncontrolled proliferation of Langerhans cells. We report a case of a 5-years old girl with left post auricular swelling, otalagia and otorrhea of 2 month duration, High resolution computed tomography of temporal bone show destructive expanding tissue density mass. Apparent diffusion coefficient is 1.08×10?³ mm²/s in diffusion weight magnetic resonance imaging .Post auricular incision revealed a pinkish, firm granulomatous mass occupied middle ear and mastoid Histopathological examination revealed a mixture of Langerhans histocytes and eosinophils. CD1 and S100 are positive in mmunohistochemistry.

Keywords: Histiocytosis; Temporal bone; Diffusion weight MRI; CT temporal bone

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