Journal of Otology & RhinologyISSN: 2324-8785

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Research Article, J Otol Rhinol Vol: 6 Issue: 4

Postlaryngectomy Pharyngocutaneous Fistula:Analysis of Possible Risk Factors

Bilici S*, Gokduman AR and Yigit O

Department of Otorhinolaryngology and Head and Neck Surgery, University of Health Sciences, Istanbul Training and Research Hospital, Turkey

*Corresponding Author : Suat Bilici, MD
Department of Otorhinolaryngology & Head and Neck Surgery, University of Health Sciences, Istanbul Training and Research Hospital
Abdurrahman Nafiz Gurman, Street No: 1, Postal code: 34098, Istanbul, Turkey
Tel: 0532 233 46 00
Fax: +902126320063

Received: June 13, 2017 Accepted: June 28, 2017 Published: July 05, 2017

Citation: Bilici S, Gokduman AR, Yigit O (2017) Postlaryngectomy Pharyngocutaneous Fistula:Analysis of Possible Risk Factors. J Otol Rhinol 6:4. doi: 10.4172/2324-8785.1000321


Objective: The aim of this study was to analyse factors that predispose patients to pharyngocutaneous fistula (PCF) in total laryngectomy, with a focus on intraoperative primary tracheooesophageal fistula (TEF) with voice prosthesis and anti-reflux prophylaxis.
Methods: This retrospective cohort included 77 patients who underwent total laryngectomy (TL). Potential risk factors included intraoperative primary TEF with voice prosthesis, anti-reflux prophylaxis, previous radiotherapy (RT), diabetes mellitus, concurrently neck dissection and tumour stage.
Results: The global PCF rate was 46.3%. No statistically significant difference was noted between the fistula positive and negative groups for these parameters, except for hospitalisation time.
Conclusion: Anti-reflux prophylaxis was not significantly associated with the incidence of PCF. Primary TEF and voice prosthesis did not increase the incidence of PCF.

Keywords: Pharyngocutaneous fistula; Voice prosthesis; Anti-reflux prophylaxis; Trachea-oesophageal fistula

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