Journal of Otology & RhinologyISSN: 2324-8785

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Case Report, J Otol Rhinol Vol: 5 Issue: 6

Skull Base Metastasis from Follicular Thyroid Carcinoma: A Case Report and Review of the Literature

London Jr NR1, Gniadek TJ2, Bishop J2 and Ramanathan Jr M1*
1Department of Otolaryngology - Head and Neck Surgery, Johns Hopkins, Baltimore, MD, USA
2Department of Pathology, Johns Hopkins, Baltimore, MD, USA
Corresponding author : Ramanathan M
MD, Johns Hopkins Department of Otolaryngology - Head and Neck Surgery, 601 N. Caroline Street, 6th Floor, Baltimore, MD, USA, 21287
Tel:
(443) 287-2000
Fax: (410) 614-8610
E-mail: [email protected]
Received: November 04, 2016 Accepted: November 10, 2016 Published: November 17, 2016
Citation: London NR, Gniadek TJ, Bishop J, Ramanathan M (2016) Skull Base Metastasis from Follicular Thyroid Carcinoma: A Case Report and Review of the Literature. J Otol Rhinol 5:6. doi: 10.4172/2324-8785.1000299

Abstract

Metastasis to the skull base is rare but occurs most frequently with breast and prostate cancer. Suspicion for skull base metastasis should be elevated in patients with a history of cancer and unexpected ipsilateral cranial nerve findings. In this case report, we present a highly aggressive case of poorly differentiated follicular thyroid carcinoma with the unanticipated finding of metastatic spread the skull base. This case is unique from others given the extensive involvement of the pelvis, larynx, and aggressive infiltration of multiple skull base sites including the cavernous sinus, Meckel’s Cave, foramen ovale, and the floor of the right middle fossa. We conclude that skull base metastasis should be on the differential diagnosis for a patient with a history of aggressive thyroid cancer and new pathologic ipsilateral cranial nerve physical exam findings.

Keywords: Skull base metastasis; Follicular thyroid carcinoma; Thyroid cancer

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