Research Article, J Spine Neurosurg S Vol: 0 Issue: 0
Postoperative Ambulatory Status Predicts Survival in Patients with Glioblastoma Multiforme
Leif-Erik Bohman1, James H Stephen1, Rohan Ramakrishna2, James M Schuster1 and Neil R Malhotra1* | |
1Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA, USA | |
2Department of Neurological Surgery, University of Washington, Seattle, WA, USA | |
Corresponding author : Neil R Malhotra, MD Assistant Professor, Department of Neurosurgery, University of Pennsylvania, 3 Silverstein - 3400 Spruce Street, Philadelphia, PA 19104, USA E-mail: nrm@uphs.upenn.edu |
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Received: April 12, 2013 Accepted: May 10, 2013 Published: May 31, 2013 | |
Citation: Bohman LE, Stephen JH, Ramakrishna R, Schuster JM, Malhotra NR (2013) Postoperative Ambulatory Status Predicts Survival in Patients with Glioblastoma Multiforme. J Spine Neurosurg S1. doi:10.4172/2325-9701.S1-001 |
Abstract
Postoperative Ambulatory Status Predicts Survival in Patients with Glioblastoma Multiforme
Much attention in the surgical literature has emphasized the survival benefit of maximal resection in patients with Glioblastoma Multiforme (GBM). Preoperative functional status has also been long recognized as a major factor on prognosis, but less attention has been paid to the importance of postoperative neurological function on survival. Our study sought to investigate the survival impact of a particularly severe postoperative motor deficit, the loss of functional ambulation, on survival in patients with newly diagnosed primary GBM.