Clinical Dermatology Research JournalISSN: 2576-1439

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Langerhans cell histiocytosis associated with Helicobacter pylori infection

Bashir AHH, Lamyaa AM, Al Hassan AM

University of Juba, Sudan
Jabir AbuEliz Diabetic Centre, Sudan

: J Clin Exp Dermatol Res


Langerhans cell histiocytosis (LCH) is defined as a clonal proliferation of Langerhans phenotypiclike cells. Letterer-Siwe disease is the most common and serious of these entities, affecting mainly infants up to two years of age. We report an interesting, previously misdiagnosed and relapsing case of adult skin limited to LCH in a 25 years old female patient presented with well-defined erythematous, dry scaly plaques in the face, trunk and extremities for 10 years duration, and then remains stable over the time. The case is diagnosed and confirmed histopathologically, considered to be the second case of LCH and first case as adult Letterer Siwe been reported in Sudan.


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