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Journal of Otology & RhinologyISSN: 2324-8785

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Case Report, J Otol Rhinol Vol: 4 Issue: 1

Sestamibi Localization of a Parathyroid Adenoma in the Presence of a Thymoma: a Case Report and Review of the Literature

Andrew M. Hinson1,2, H. Gareth Tobler3, Chien Chen4, Tracy L.Yarbrough6, Donald L. Bodenner2,5, Brendan C. Stack, Jr.1,2*
1Department of Otolaryngology-Head and Neck Surgery, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
2University of Arkansas for Medical Sciences Thyroid Center, Little Rock,Arkansas, USA
3Division of Cardiothoracic Surgery, University of Arkansas for Medical Sciences,Little Rock, Arkansas, USA
4Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
5Department of Geriatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
6Dept of Pharmacology & Physiology, George Washington University,Washington, DC, USA
Corresponding author : Brendan C. Stack, Jr.
MD, 4303 W. Markham St. #543, Little Rock, Arkansas 72205, USA
Tel: 501-686-5140; Fax: 501-686-8029
E-mail: [email protected]
Received: August 18, 2014 Accepted: October 04, 2014 Published: January 27, 2015
Citation: Hinson AM, Tobler HG, Chen C, Yarbrough TL, Bodenner DL, et al. (2015) Sestamibi Localization of a Parathyroid Adenoma in the Presence of a Thymoma: A Case Report and Review of the Literature. J Otol Rhinol 4:1. doi:10.4172/2324-8785.1000205

Abstract

Sestamibi Localization of a Parathyroid Adenoma in the Presence of a Thymoma: a Case Report and Review of the Literature

Preoperative localization in the surgical management of primary hyperparathyroidism is complicated by widely variable parathyroid gland anatomy, coexisting thyroid pathology, incidence of supernumerary and ectopic parathyroid glands, and limitations of targeted imaging studies. Technetium 99mTcsestamibi scans have decreased accuracy, sensitivity and specificity in the presence of multi-gland parathyroid disease. A number of reports suggest that thymomas, which also show increased sestamibi uptake, are potential sources of false positives on 99mTc-sestamibi scans. Herein, we describe a thymoma in association with a parathyroid adenoma complicating localization of hyperfunctional parathyroid tissue. We review the literature of concurrent pathology between parathyroid adenomas and thymomas paying particular attention to how these cases present on preoperative 99mTcsestamibi scans.

Keywords: Thymoma; Parathyroid adenoma; Hyperparathyroidism; Sestamibi

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