Journal of Womens Health, Issues and CareISSN: 2325-9795

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Editorial, J Womens Health Issues Care Vol: 2 Issue: 2

Women in Cardiovascular Clinical Trials

Wesley T. O’Neal1, Taylor E. Edwards1, Chelsea S. DiMartino1 and Jimmy T. Efird1,2*
1Department of Cardiovascular Sciences, East Carolina Heart Institute, Greenville, NC, USA
2Center for Health Disparities Research, Brody School of Medicine, East Carolina University, Greenville, NC, USA
Corresponding author : Jimmy T. Efird
Center for Health Disparities Research, Brody School of Medicine, East Carolina University, 115 Heart Drive, Greenville, NC 27834, USA
+1 650 248 8282; Fax: +1 252 744 5539
Received: March 11, 2013 Accepted: March 12, 2013 Published: March 15, 2013
Citation: O’Neal et al. (2013) Women in Cardiovascular Clinical Trials. J Womens Health, Issues Care 2:2 doi: 10.4172/2325-9795.1000e106


Women in Cardiovascular Clinical Trials

Between 1980 and 2000, the age-adjusted death rate due to coronary heart disease (CHD) decreased by 48%. The optimization of medical therapies (OMT) and revascularization procedures such as percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) has accounted for 50% of the decline. While mortality rates for CHD have not declined equally for men and women, recent randomized clinical trials have not addressed gender differences regarding the efficacy of therapeutic interventions. Historically, women have been underrepresented in clinical trials of cardiovascular disease.

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