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Previous Issue      
Volume 3, Issue 1
Editors & Editorial Board Members  
J Nanomater Mol Nanotechnol 2014, 3:1   
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Nanotechnology in Wood and Wood-Composite Materials   Editorial
Hamid Reza Taghiyari
J Nanomater Mol Nanotechnol 2014, 3:1    doi: 10.4172/2324-8777.1000e106
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Nanotechnology in Wood and Wood-Composite Materials

Wood is a natural, biodegradable, and renewable material that canbe used in many applications, including structural members, ornamental objects, aerospace technology, etc. Its low thermal and electrical conductivity coefficients have made it unique for specific purposes since the creation of humanity. However, some of its other features are quite bothering such as its deterioration by a variety of fungi and insects, its susceptibility to fire, as well as the dimensional instability to water absorption. Over the past few decades, nanotechnology was utilized in many sciences and it was used to improve the quality of many materials, including wood and wood-composites.
 

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IG-001 - A Non-Biologic Nanoparticle Paclitaxel for the Treatment of Solid Tumors   Research Article
Kouros Motamed, Yin Goodman, Larn Hwang, Chao Hsiao and Vuong Trieu
J Nanomater Mol Nanotechnol 2014, 3:1    doi: 10.4172/2324-8777.1000136
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IG-001 - A Non-Biologic Nanoparticle Paclitaxel for the Treatment of Solid Tumors

nab-paclitaxel (Abraxane®)—a Cremophor-free, albumin-bound, nanoparticle form of paclitaxel—though a breakthrough in paclitaxel formulation, has inherent problems associated with any biologics. IG-001 (Genexol-PM®), a polymeric micellar formulation forms nanoparticles with paclitaxel containing a hydrophobic core and a hydrophilic shell and is being developed as the next generation nanoparticle paclitaxel. Its target indications are solid tumors including Breast, Lung, Ovarian, Bladder, Melanoma and Pancreatic cancers. Similar to nab-paclitaxel, due to its very fast dissolution in plasma, high tumor/plasma ratio, and dose-proportional PK, IG-001 is a superior alternative to Taxol®. Moreover, despite a lack of serum albumin in its formulation, IG-001 takes full advantage of its ability to rapidly deliver paclitaxel to the targeted tissue via an albuminmediated transport, as previously described for nab-paclitaxel.

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Zn-Ga/Zn-In Layered Double Hydroxides:Synthesis, Characterization and Adsorption to Methyl Orange   Research Article
Dongxiang Li, Xin Qian, Qianru Li, Jinrong Wu, Jikuan Zhao and Wanguo Hou
J Nanomater Mol Nanotechnol 2014, 3:1    doi: 10.4172/2324-8777.1000137
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Zn-Ga/Zn-In Layered Double Hydroxides:Synthesis, Characterization and Adsorption to Methyl Orange

Zn-Ga and Zn-In layered double hydroxides (LDHs) were synthesized by coprecipitation method and characterized by powder X-ray diffraction (PXRD), scanning electron microscopy (SEM), FTIR and BET analysis. The particles of Zn-Ga/Zn-In LDHs are typical hexagonal layered nanodisks or soft nanoflakes with different size and thickness as changing Zn/Ga (In) molar ratio in the preparation. Zn-Ga LDHs have high adsorption ability to methyl orange in water, while calcined Zn-Ga LDHs can adsorb methyl orange via a slow reconstruction process. Zn-In LDHs have not adsorption capability to methyl orange, but calcined Zn-In LDHs show weak adsorption to methyl orange through reconstruction.
 

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Nanocarriers Based Oral Insulin Delivery   Short Communication
Lotika Bajaj and Bhupinder Singh Sekhon
J Nanomater Mol Nanotechnol 2014, 3:1    doi: 10.4172/2324-8777.1000138
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Nanocarriers Based Oral Insulin Delivery

Successful oral administration of protein drugs remains an obscure challenge. In this context, oral insulin delivery has always been a significant challenge for pharmaceutical researchers and considerable efforts are being made to deliver insulin orally. Oral insulin therapy seems to have progressed with nanotechnology research, allowing for several types of encapsulations to bypass the gastric acidic environment. Nanoparticles protect insulin against degradation and facilitate the uptake of insulin (associated or not associated to the nanoparticles) through a paracellular or a transcellular pathway. In oral insulin, the mechanism involves various nanoparticle encasings bound to insulin delivery. Continuous comparisons of in vitro and in vivo studies are essential to develop oral insulin delivery systems in near future.
 

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Application of TiO2- Zeolite Nano-Composite for Photodegradation of 4-Chlorophenol   Research Article
Hossein Faghihian, Heibat Allah Raeiesi
J Nanomater Mol Nanotechnol 2014, 3:1    doi: 10.4172/2324-8777.1000139
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Application of TiO2- Zeolite Nano-Composite for Photodegradation of 4-Chlorophenol

In this research, nanoparticle of b-zeolite was synthesized by solgel method and titanium dioxide was prepared by hydrolysis of titanium isopropoxide. To prepare TiO2-zeolite nano-composite, the synthesized b-zeolite was mixed with requisite amount of TiO2 dispersed in acetone. The mixture was thoroughly homogenized, dried at 110˚C and calcined at 400˚C. The nano composite was characterized by XRD, SEM and TEM techniques. Photocatalytical activity of the nano-composite for degradation of 4-chlorophenol was studied under UV irradiation. The influence of effective parameters including; pollutant initial concentration, amount of TiO2, pH and irradiation time were studied and optimized. The results showed that the synthesized nanocomposite in terms of rate and degradation efficiency was better than bare TiO2. The optimal degradation was obtained at pH=2.5 and initial concentration of 100 mg.L-1 and 10% TiO2 loading. The photocatalyst was recyclable and retained its initial properties after four regeneration cycles.
 

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From Quantum-Dot Nanorings to Polyacetylene via Small Annulenes: A Full Configuration Interaction Description Based on an Extended Hubbard–Su-Schrieffer-Heeger Model   Research Article
Ioan Bâldeaand Horst Köppel
J Nanomater Mol Nanotechnol 2014, 3:1    doi: 10.4172/2324-8777.1000140
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From Quantum-Dot Nanorings to Polyacetylene via Small Annulenes: A Full Configuration Interaction Description Based on an Extended Hubbard–Su-Schrieffer-Heeger Model

Quantum chemical approaches to molecules — like the annulenes (cyclic polyenes CNHN, where N is an integer) considered here — usually examine the impact of electron-electron interaction at frozen molecular geometries within approaches based on a single (or a few) Slater determinant(s). In the solid-state community, polyacetylene, their asymptotic limit [(CH) = limN→∞CNHN] is oftentreated as a statically dimerized chain within a single-electron picture (static Su-Schrieffer-Heeger (SSH) model). More recent studies on quantum-dot nanorings employed SSH models extended to embody quantum phonon dynamics and Hubbardtype electron-electron interaction terms, which are treated exactly within a full configuration (CI) description. In the present paper we show that this full CI extended Hubbard-SSH framework provides a unitary description of important properties both of small annulenes (cyclobutadiene, benzene, and octatetraene) and of polyacetylene based on a few N-independent model parameters. These results emphasize the importance of the full CI description; provided that a few important terms are retained, a schematic description of the interaction does not preclude a reasonable description.

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