Clinical Oncology: Case Reports

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Bilateral Primary Cerebellopontine Angle Lymphoma Mimicking NF-2: A Rare Case Report with Review of Literature

Background and Importance: Primary CNS lymphomas (PCNSL) are a rare entity. Even rarer is CNS lymphomas of bilateral Cerebellopontine Angle (CPA) mimicking NF-2. The rarest form is bilateral cerebellopontine lymphomas extending into Internal auditory meatus along with multiple other CNS lesions. Management in this regard can only be done after definitive diagnosis. Symptomatic lesions leading to surgery hardly find description in literature.

Clinical Presentation: We present a 55 year old male with the rarest form PCNSL presenting with multiple cranial nerve deficits and involving bilateral CPA. Surgery confirmed the diagnosis in otherwise presumed case of NF-2. Management pearls along with histological analysis are highlighted.

Conclusion: We assume CNS lymphomas are a great mimicker and biopsy proven diagnosis and change the course of management with extremely good outcomes.

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