Journal of Clinical & Experimental Radiology

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Current Status of Gadolinium Retention in the Brain

Gadolinium (Gd3+) based contrast agents previously demonstrated safe administration and were associated with minimal events of adverse reactions until NSF and gadolinium deposits were found in the brain. Gadolinium is a paramagnetic earth lanthanoid element with a ferromagnetic property that is suitable for intravenous administration. Recently, a series of studies raised their concern over the higher risk of developing NSF when administering nonionic linear agents such as gadodiamide and gadoversetamide

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