Journal of Nanomaterials & Molecular NanotechnologyISSN: 2324-8777

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Dietary Intake of (-)-Epigallocatechin-3-gallate against Aging and Cancers: Nanoencapsulation of Multi- Rings Still Requires New Rounds!

Dietary Intake of (-)-Epigallocatechin-3-gallate against Aging and Cancers: Nanoencapsulation of Multi- Rings Still Requires New Rounds!

Polyphenols, a superfamily of naturally occurring phytochemicals, are gaining popularity because of their potential health benefits. Indeed, as demonstrated in ex-vivo and in non-primates models, they exert variable and pleiotropic biological effects (e.g. anti- or pro-oxidant, anti-inflammatory, anti-tumoral, anti-aging) depending on their structure and physicochemical features. However, these effects are often limited Carnauba wax by their overall unstability and bioavailability. The fact that some polyphenols act either as anti-oxidants (e.g. against aging) or as pro-oxidants (e.g. against tumors/cancers), remain an unsolved paradigm. Interestingly, emergent studies suggest that nano-encapsulated polyphenols might overcome some limitations frequently observed with dietary bulk-polyphenols (e.g. bioavailability, pharmacokinetics, targeting, efficacy, toxicity and safety), subsequently potentiating their biological effects. In this context, the case of (-)-epigallocatechin- 3-gallate (EGCG) is quite intriguing.

Special Features

Full Text

View

Track Your Manuscript

Media Partners

GET THE APP