Journal of Genetic Disorders & Genetic Reports ISSN: 2327-5790

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Lipoprotein Glomerulopathy: Molecular Characterization of Three Italian Patients and Literature Survey

Lipoprotein Glomerulopathy: Molecular Characterization of Three Italian Patients and Literature Survey

Lipoprotein glomerulopathy (LPG) is a rare kidney disease, mainly reported in Asian subjects, linked with rare APOE gene mutations resulting in a structurally abnormal Apolipoprotein E (ApoE), the plasma accumulation of lipoprotein remnants and the formation of lipid thrombi in glomerular capillaries. This study reports the molecular characterization of three unrelated Italian patients with long standing LPG.

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