Abdul Mutalib Md Jani Author
Subjects of specialization
Affiliation
Surface Chemistry, Materials Science, Nanotechnology, Aluminium, Anodization.
Chemistry Department, Faculty of Applied Sciences, Universiti Teknologi MARA (UiTM), 02600 Arau, Perlis, Malaysia
Abdul Mutalib Md Jani working in Chemistry Department, Faculty of Applied Sciences, Universiti Teknologi MARA (UiTM), 02600 Arau, Perlis, Malaysia. Abdul Mutalib Md Jani has an area of research interest in the field of Nanomaterials fabrication and surface manipulation. Application of nanostructured materials in drug delivery and separation, Surface Chemistry, Materials Science, Nanotechnology, Aluminium, Anodization.
Research Article Subscription
Author(s): Abdul Hadi Mahmud, Abdul Mutalib Md Jani and Mohd Tajudin Mohd Ali
The present study describes the synthesizing and attaching of betulinic acid-aminopropyl triethoxysilane (BA-APTES) on top of the nanoporous alumina (NA) surface. The NA was fabricated by using electrochemical anodization process under an applied voltage of 40 V for 20 hours resulting in average pore size of 45 nm characterized by Scanning Electron Microscope (SEM). The well-recognized therapeutic compound, betulinic acid (BA) was first extracted from the bark of Melaleuca cajuputi plant and further purified by column chromatography. The purified BA was incorporated with APTES using 1-hydroxybenzotriazole hydrate (HOBt) and O-(Benzotriazol-1-yl)-N,N,N’-tetramethyluronium hexafluorophosphate (HBTU) as a peptide coupling agent. The synthesized BA-APTES was silanized on top of the fa... view moreĀ»