Journal of Pharmaceutical Sciences & Emerging DrugsISSN: 2380-9477

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Andrea d Amico Author

Subjects of specialization
Pharmacology, Pharmaceutical Sciences, Medicinal Chemistry, Drag reduction, Drug Therapy

Affiliation
Department of PET Diagnostic, Faculty of Diagnostic, Maria Sklodowska Curie Memorial Cancer Center, Institute of Oncology, 44-101 Gliwice, Poland

Biography

Department of PET Diagnostic, Faculty of Diagnostic, Maria Sklodowska Curie Memorial Cancer Center, Institute of Oncology, 44-101 Gliwice, Poland.  One of his references is, "Nanabala R, Anees MK, Sasikumar A, Joy A, Pillai MR, et.al. (2016) Preparation of [68Ga]PSMA-11 for PET-CT imaging using a manual synthesis module and organic matrix based 68Ge/68Ga generator. Nucl Med Biol 43: 463-469."


Publications

Research Article Open Access

Synthesis and Quality Control of 68Ga-PSMA PET/CT Tracer used in Prostate Cancer Imaging and Comparison with 18F-Fluorocholine as a Reference Point

Author(s):

Marcin Szydlo*, Dawid Pogoda, Tomasz Kowalski, Mateusz Pociegiel, Michał Jadwinski and Andrea d Amico

The clinical usefulness of choline-based PET/CT tracers (11C-Choline and 18F-Fluorocholine) in prostate cancer recurrence imaging is well established. However, choline uptake is not increased in a considerable number of patients. In 2012 was proposed the new prostate-specific PET radio ligand PSMA 68Ga-labeled, with superior sensibility and specificity than choline-based tracers. This work has as aim to describe the procedures for labeling PSMA ligands and its quality control procedures as a medicinal product and its comparison with 18F-fluorocholine synthesis and quality control procedures. Both the manual and automated synthesis methods for 68Ga-PSMA were taken into account and set of a quality control methods based mainly on chromatographic and spectromet... view more»

DOI: 10.4172/2380-9477.1000126

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