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Hindi Dental Health: Current ResearchISSN: 2470-0886
Blume JD Author
Subjects of specialization
Affiliation
Biostatistics
Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
Biography
Dr. Blume is an Associate Professor in Biostatistics and Biomedical Inforamatics, in the School of Medicine, Vanderbilt University. He is the Director of Graduate Studies in the Department of Biostatistics and Co-Director of the Big Biomedical Data Science Ph.D. program. Professor Blume received his Ph.D. in Biostatistics from the John Hopkins School of Public Health, where he was the recipient of a National Eye Institute Traineeship in Clinical Trials. He has extensive experience in the development, operation, analysis, and methodological aspects of Clinical Trials.
Publications
Research Article Open Access
Estimation of Anesthetic Success Rates: The Efficacy of Articaine versus Lidocaine
Author(s): Smith DK, Smith LE and Blume JD
Purpose: Multiple randomized controlled trials have compared the efficacy of 2% lidocaine with 1:100,000 epinephrine to 4% articaine with 1:100,000 epinephrine. However, there is still uncertainty about expected success probabilities with various anesthetic modalities that needs to be addressed in the literature.
Methods: A search of PubMed and Google yielded over 200 potential articles. 13 randomized controlled trials met the eligibility criteria for inclusion in the analysis. Analyses compared lidocaine and articaine in teeth with and without a diagnosis of pulpitis for maxillary infiltration, mandibular buccal infiltration, and inferior alveolar nerve block (IANB).
Results: Articaine demonstrated superior anesthetic efficacy regardless of the type of injection administered ... view more»
Google Scholars / Researchers Sites
