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Hindi Journal of Nanomaterials & Molecular NanotechnologyISSN: 2324-8777
Carola Kryschi Author
Subjects of specialization
Affiliation
Nanoscience, Nanotubes, Nanomaterials, Nanotechnology, Nanoparticles.
Instituto de Investigaciones Fisicoqu
Biography
Carola Kryschi currently works at the Department of Chemistry and Pharmacy, Friedrich-Alexander-University of Erlangen-Nürnberg. Carola does research in Materials Science and Physical Chemistry. Their current project is '1. Design and characterization of magnetoplasmonic Au-iron oxide nanoparticles as dose enhancer in radiotherapy and for drug delivery.
Publications
Research Article Subscription
Oxidized Silicon Nanoparticles and Iron Oxide Nanoparticles for Radiation Therapy
Author(s): Stefanie Klein, Anja Sommer, Maria L. Dell’Arciprete, Marc Wegmann, Susanne V. Ott, Luitpold V. R. Distel, Winfried Neuhuber, Mónica C. Gonzalez, and Carola Kryschi
Oxidized Silicon Nanoparticles and Iron Oxide Nanoparticles for Radiation Therapy
Our research objective is to develop superparamagnetic iron oxide nanoparticles and silicon nanoparticles as radiosensitizers for cancer therapy. After internalization by breast tumor cells and irradiation with X-rays, the nanoparticles were observed to enhance the oxidative stress in tumor cells. While silicon nanoparticles increase the reactive oxygen species production under X-ray treatment due to their incompletely oxidized surface, positively charged amino-functionalized silicon nanoparticles enhance the formation of mitochondrial reactive oxygen species formation because of ... view more»
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