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Hindi Journal of Pharmaceutics & Drug Delivery ResearchISSN: 2325-9604
Daniel Scott Author
Subjects of specialization
Affiliation
Lipophilic Polymer Additives
Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 South Limestone, Lexington, KY 40536, USA
Biography
Dr. Daniel Scott is a University Research Chair in Global Change and Tourism and the Director of Interdisciplinary Centre on Climate Change at the University of Waterloo (Canada). He has been a contributing author and expert reviewer for the United Nations Intergovernmental Panel on Climate Change Third, Fourth, and Fifth Assessment Reports and is currently on the Advisory Committee to the United Nations Environment Programme lead Global Partnership for Sustainable Tourism. Received the award for scholarly distinction from the Canadian Association of Geographers in 2018.
Publications
Research Article Open Access
Block Copolymer Crosslinked Nanoassemblies Co-entrapping Hydrophobic Drugs and Lipophilic Polymer Additives
Author(s): Daniel Scott and Younsoo Bae
Block Copolymer Crosslinked Nanoassemblies Co-entrapping Hydrophobic Drugs and Lipophilic Polymer Additives
Block copolymer crosslinked nanoassemblies (CNAs) were synthesized to investigate their patterns of entrapping and releasing an anticancer drug (17-AAG) in the presence of a lipophilic polymer additive (polylactic acid: PLA) in the core. The CNAs were prepared by crosslinking poly (ethylene glycol)-poly (aspartate hydrazide) (PEG-Hyd) block copolymers through an amide bond. The CNAslocked in the particle size after co-entrapping 17-AAG and PLA (< 50 nm in diameter). PLA with various molecular weights (3.4, 6, and 7.5 kDa) was used as polymer additives that are s... view more»
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