Debopriya Ghosh Author

Short Communication Open Access

Effects of microgravity on human induced pluripotent stem cell derived cardiomyocytes: A comprehensive review

Author(s):

Debopriya Ghosh

For the future of regenerative medicine era, the efficient generation of cardiomyocytes from human pluripotent stem cells (hiPSC- CM) is very critical. Some extreme environment like microgravity and 3D culture can profoundly modulate cell proliferation and survival in efficient manner. The International Space Station (ISS) becoming commonplace for utilizing the space environment for better understanding the risks and benefits of human space flight along with role of extreme environment on cellular level. This comprehensive review literature includes some modern studies on effect of microgravity on cellular and genetic level of cardiomyocyte. Human instigated pluripotent immature microorganism inferred cardiomyocytes (hiPSC-CMs) were used to consider the impacts of microgravity on cell-l... view more»

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