Clinical Oncology: Case Reports

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Dhanlaxmi Shetty Author

Subjects of specialization
pre-natal, post-natal and cancer genetics

Affiliation
Department of Cancer Cytogenetics, Advanced Centre for Training, Research and Education in Cancer (ACTREC), Tata Memorial Centre, Kharghar, Navi Mumbai, India

Biography

Dr. Dhanlaxmi Shetty is a cytogeneticist. Currently she is the Scientific Officer-E and Officer-in-charge at the Cancer Cytogenetics Department, Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Tata Memorial Centre. Dr. Shetty has over 10 years of experience in pre-natal, post-natal and cancer genetics from three NABL and CAP accredited laboratories. She has over 30 publications in peer-reviewed, indexed journals and has been involved as PI and Co-PI for several projects at ACTREC. She has also presented her work in several national and international conferences and is a member of many genetic bodies across India.


Publications

Case Report Open Access

Isochromosome i(9)(q10): A Rare Chromosomal Aberration in B-cell Acute Lymphoblastic Leukemia

Author(s):

Yogita Rohil, Dhanlaxmi Shetty, Hasmukh Jain and LR Nayak (India)

Cytogenetic analysis in Acute Lymphoblastic Leukemia (ALL) reveals number of non-random chromosome abnormalities which play an important role in prognostication of patients. Isochromosomes are uncommonnon-random chromosome aberrations in acute lymphoblastic leukemia (ALL) and prognostic significance of the presence of isochromosome(s) remains to be well established. The incidence of i(9q) in ALL is very low. Majority of the patients are older than 10 years and the aberration occurs in combination with other chromosomal abnormalities. We present two cases of adult BALL with i(9q) as one of the cytogenetic aberration at diagnosis. Case 1 patient was given standard treatment protocol and complete remission was achieved at the end of induction phase II therapy a... view moreĀ»

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