Hawk Author
Subjects of specialization
Affiliation
Diagnostic Radiology, radiography, CT
Community Hospital Cancer Center, 1440 East County Line Road Indianapolis, IN 46227, USA
Dr. Hawk is a working in the Community Hospital Cancer Center, USA. Over the experience in the field of Metastatic adrenocortical carcinoma; Immunotherapy; Pembrolizumab, Dr. Hawk publish various articles in quality journals.
Case Report Open Access
Author(s): Lindsey Addington*, Hagman Thomas, Hawk, Nicole CMA and Pablo Bedano (USA)
Adrenocortical carcinoma (ACC) is a rare cancer with limited effective treatment options and poor prognosis. ACC incidence is 1 to 2 cases per million making randomized clinical trials difficult to conduct. The current standard first line treatment for metastatic ACC showing tumor response and improved progression free survival (PFS) is etoposide-doxorubicin-cisplatin (EDP) plus mitotane. Multiple efforts to find a targeted treatment for ACC have not shown impressive responses. Immunotherapy agents such as checkpoint inhibitors programmed cell death – 1 receptor (PD-1) and programmed cell deathligand 1 have shown significant responses in multiple malignancies including melanoma, non-small-cell-lung cancer, Hodgkin’s lymphoma to name a few. We present a case of a female patie... view moreĀ»