Hossam Khalifa2 Author

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Effects of extended abstinence on cognitive functions in Tramadol dependent patients: a cohort study

Author(s):

Shehab H Hassaan1,2*, Hossam Khalifa2 and Alaa M Darwish2

Background: Some pieces of the literature report impaired cognitive functioning in tramadol dependence. Whether extended abstinence improves cognitive functioning or not is not well studied. We aimed to measure the change in cognitive functioning following complete abstinence among individuals with tramadol dependence.
Methods: Eighty-three male tramadol-dependent (TD) and 57 matched healthy controls participated in this study. Cognitive functions were assessed using: The Trail making test (TMT), Wechsler Memory Scale-Revised (WMS-R), and Wechsler Adult Intelligence Scale (WAIS). Patients were assessed in the first week immediately after the end of the in-patient treatment program (T1), and after six months of sustained abstinence (T2).
Results: At T1, the TD group showed ... view more»

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