Ivan L. Quevedo Author

Short Communication Open Access

Radiation-Therapy Effects On Bone Hydroxyapatite Structure

Author(s):

Ivan L. Quevedo

Radiotherapy is associated with radiographically detected osteoporosis. The precise pathophysiology is not completely known yet. Hydroxyapatite (Hap, Ca₁₀(POâ‚„)₆(OH)â‚‚) is the mineral component of the bone, and it can form chemical and mechanical bonds directly with living tissues, and with bone-implant interfaces as well. The aim of this research was to study the influence of external radiotherapy in the Hap ultrastructure. The experimental study was carried out on a section of bone from a human humerus, extracted from a male donor (50 years old). The bone tissue sample was irradiated with a telecobalt therapy equipment (Phoenix 2000), applying 35 fractions of 2 Gray each from Monday to Friday, until completing 70 Gray. The energy of the radiation and ti... view more»

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