Jennifer G. Plebani Author
Subjects of specialization
Affiliation
role of stress and craving on cocaine and alcohol use, , behavioral pharmacology,health behaviors during substance abuse treatment
Research Assistant Professor of Psychology in Psychiatry, University of Pennsylvania, 3900 Chestnut Street, Philadelphia, PA 19104, USA
Dr. Plebani has conducted research on the treatment of addictive disorders, including the evaluation of behavioral interventions for nicotine dependence, and pharmacotherapies for the treatment of cocaine dependence and alcohol dependence. Her current research interests include investigating the mechanisms of action of promising pharmacotherapies in human laboratory studies, as well as clinical trials combining behavioral interventions such as contingency management with promising pharmacotherapies for cocaine, alcohol and opiate dependence.
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Author(s): Jennifer G. Plebani
Running Over the Same Old Ground: What’s Missing in Cocaine Clinical Pharmacotherapy Trials?
In over two decades of cocaine treatment research, countless pharmacotherapies have been tested, without a single medication approved for the treatment of cocaine dependence. A short and entirely incomplete list of tested medications includes: olanzapine, valproate, coenzyme Q10, L-carnitine, cabergoline, reserpine, tiagabine, amantadine, propranolol, selegiline, modafinil, sertraline, disulfiram, baclofen, and citicoline. Setting aside the very real possibility that none of the medications tested to date is actually efficacious for treating cocaine dependence, there are thre... view more»