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Hindi Clinical Oncology: Case Reports
Jeremy Drees Author
Subjects of specialization
Affiliation
cancer, cancer oncology, Carcinogenesis
MD Biosciences Inc., Oakdale, MN, Canada, U.S.A.
Biography
Jeremy Drees, Ph.D., served as a Senior Scientist and Study Director in a contract research organization (MD Biosciences/MLM Medical Labs), where he developed and validated multiple disease models and directed over 100 pre-clinical projects with a focus on inflammation, fibrosis, metabolism, cancer, and autoimmunity. During this time, he also served as the scientific lead for developing unique flow cytometry tests for exploratory clinical endpoints. He received his PhD from the University of Minnesota Microbiology, Immunology, and Cancer Biology program where he investigated the potential of bacterially-delivered immunotherapeutics for cancer treatment.
Publications
Case Report Open Access
Orally Administered Multiple Dose Saltikva (Salmonella-IL2) in Conjunction with Folfirinox in a Patient with Stage IV Pancreatic Cancer: A Case Report
Author(s): Gerald Batist, Joo Yeoun Park, Jeremy Drees, Takashi Kangas and Daniel Saltzman* (USA)
Compassionate use of Saltikva was sought for a patient with stage 4, metastatic pancreatic cancer. Approval was granted for an n=1 multiple dose (every 2 week) trial with concomitant FOLFIRINOX. Now, at 15 months, this patient has not experienced any toxicity to Saltikva, continues therapy, has normalized CA19-9 levels, maintained her immunologic cell populations despite cytotoxic chemotherapy, demonstrated a strong NK cell response, and has a radiologic regression of metastatic tumor burden with a complete absence of tumor activity by PET scan.
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