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Hindi Clinical Oncology: Case Reports
Kanji Katayama (Japan) Author
Subjects of specialization
Affiliation
Colorectal Cancer, Surgery, Colorectal Surgery, Surgical Oncology, Gastrointestinal Surgery, Abdominal Surgery, Surgical Gastroenterology, Cancer Surgery, Hepatobiliary, Surgery
Cancer Care Promote Center, University of Fukui, Eiheiji, Japan
Biography
Dr. Kanji Katayama, is research scientist at Cancer Care Promote Center, University of Fukui, Eiheiji, Japan. Dr. Katayama has a research interest in the field of Colorectal Cancer, Surgery, Colorectal Surgery, Surgical Oncology, Gastrointestinal Surgery, Abdominal Surgery, Surgical Gastroenterology, Cancer Surgery, Hepatobiliary, Surgery.
Publications
Case Report Open Access
Positive Response to Dual BRAF and MEK Inhibition in a Case with BRAF Mutant Anorectal Malignant Melanoma
Author(s): Hidetaka Kurebayashi*, Takanori Goi, Mitsuhiro Morikawa, Kenji Koneri, Masato Tamaki, Makoto Murakami, Yasuo Hirono and Kanji Katayama (Japan)
A 59-year-old male with the chief complaint of bloody stool underwent transanal tumor resection for an anorectal malignant melanoma. Rectal amputation and inguinal lymph node dissection were not performed due to severe anemia with platelet depression and poor general condition. After the operation, treatment with an immune checkpoint inhibitor was started. A gait disturbance was diagnosed as postoperative inflammatory neuropathy based on a nerve biopsy. As steroid treatment was necessary, the immune checkpoint inhibitor was discontinued after a single dose. Tissue diagnosis identified the BRAF gene mutation, and combination therapy with dabrafenib/trametinib was started. Abdominal contrast computed tomography on day 30 and 101 after the start of medication showed decreased right inguina... view more»
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